Health is one of the most basic needs of all human beings. The main function of the health system of any country is to provide services in this field. The reform of the health system in different countries has faced different experiences and at the same time with common goals, and in Iran we can mention some experiences, such as the establishment of health networks in the country. The beginning of the health system transformation plan in early 2014 is one of the programs that in this short period of time was seriously considered as a priority in the programs of the Ministry of Health and Medical Education. The purpose of writing this article is to analyze the health transformation plan and its consequences and effects. The main problem facing the Iranian health system was the high cost of medicine and the lack of equal access to health services, which led to the introduction of the health system transformation plan. In Iran, the Health Transformation Plan, along with important consequences such as reducing treatment costs, improving access to health services, eliminating the underdog, improving the level of health and increasing the relative satisfaction of the community that followed, has faced various challenges.