Purpose: The purpose of the present study was to design a 
model of academic vitality based on meaning and life 
expectancy with the mediation of happiness in female 
secondary school students in Hamedan city.
Materials and Methods: The research method was 
correlation and structural equations. The statistical population 
included all the female students of the second secondary 
school in Hamedan city, and the statistical sample was selected 
based on the number of items used in the questionnaires in the 
amount of 370 people using the multi-stage cluster sampling 
method. Oxford scales of academic vitality, life expectancy, 
meaning of life and happiness were used to collect data. For 
data analysis, structural equation test was used in Amos 22 
software environment.
Findings: The results showed that the meaning and hope of 
life have a direct and positive effect on the happiness and 
academic vitality of students (p<0.01). Also, happiness has a 
direct and significant effect on academic vitality (p<0.01). 
According to the results, the indirect effect of meaning and life 
expectancy on academic vitality through happiness was also 
significant (p<0.05).
Conclusion: According to the results, it can be said that hope 
and the meaning of life create motivation and a positive mental 
state and are effective in increasing happiness, and on the other 
hand, happiness plays an important role in increasing the 
freshness and vitality of the academic environment, which has 
the effect of increasing academic vitality.